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Kidney Week 2024 Medfyle Conference Coverage
Available on the Medfyle App

This activity is supported by an educational grant from Otsuka America Pharmaceutical, Inc

Welcome to

Kidney Week 2024 Medfyle Conference Coverage!

The program offer a selection of the newest and most relevant data presented at Kidney Week 2024. Enjoy this opportunity to learn about the significant advances and breakthroughs in nephrology research and care.

Pietro A. Canetta, MD, MS
Program Chair

Kidney Week 2024 Medfyle Conference Coverage Editor

Interviews

Gain valuable insights from an international panel of experts.

 

 

 

 

 

 

 

 

 

 

 

 

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Oral presentations

Missed the full presentation? Read at-a-glance summaries from a selection of oral presentations. Don’t forget to download the slides!

IgA nephropathy

Sibeprenlimab in IgAN

Barratt J, Mathur M, Liew A, et al.

Deposition of IgA-containing circulating immune complexes in the kidney is a hallmark of IgAN. Exploratory data presented at Kidney Week 2024 show the anti-APRIL antibody sibeprenlimab reduces these complexes, and correlates with reductions in UPCR.

Kidney Week 2024. Oral Session.

ENVISION Exploratory Analysis: Sibeprenlimab Reduces Circulating Immune Complexes in IgAN

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op01-barratt-sibeprenlimab-in-igan
IgA nephropathy

Iptacopan in IgAN

Rizk DV, Kollins D, Papachristofi O, et al.

Overactivation of the complement system via the alternative pathway is a key driver of IgAN pathophysiology. This interim analysis from APPLAUSE-IgAN explores the impact of iptacopan on proteinuria and complement biomarkers.

Kidney Week 2024. Oral Session.

APPLAUSE-IgAN: Interim analysis on iptacopan effect on proteinuria and complement biomarkers

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op02-rizk-iptacopan-in-igan
IgA nephropathy

Corticosteroids in IgAN

Lohana A, Akbar U, Shah SAM, et al.

This retrospective study aimed to find out whether budesonide reduces mortality and ESRD compared to prednisone in IgAN. Results presented at Kidney Week 2024 suggest budesonide may be a superior alternative for long-term management.

Kidney Week 2024. Oral Session.

Comparing Prednisone and Budesonide: Optimizing treatment in IgAN

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op03-lohana-corticosteroids-in-igan
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Posters

Read at-a-glance summaries from a selection of poster presentations.

IgA nephropathy

Zigakibart in IgAN

Barratt J, Workeneh B, Kim SG, et al.

New understanding around the pathogenesis of IgAN has led to the identification of novel targets and potential disease-specific treatments. Zigakibart is an anti-APRIL mAb under investigation – with new data suggesting clinically meaningful reductions in proteinuria.

Kidney Week 2024. Poster Session.

Zigakibart clinical trial in IgAN

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pp02-barratt-zigakibart-in-igan
IgA nephropathy

SPARTACUS: Sparsentan plus SGLT2i

Ayoub I, Tang S, Kooienga L, et al.

IgAN is a rare and progressive disease, with many clinical trials ongoing. One of these is SPARTACUS, exploring the role of a non-immunosuppressive, dual endothelin angiotensin receptor antagonist in combination with stable SGLT2i.

Kidney Week 2024. Poster Session.

SPARTACUS – interim results for concomitant sparsentan and SGLT2i in adults with IgAN

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pp03-ayoub-spartacus-sparsentan-plus-sglt2i
IgA vasculitis

Biomarkers in IgA-related disorders

Blasco M, Berrouet CC, Andrews LG, et al.

Biomarkers may distinguish IgAV pediatric patients with renal involvement from those without. GIGA-Kids set out to analyze different serological biomarkers and correlate them with disease status and severity in children with IgA-related disorders, with findings presented at Kidney Week 2024.

Kidney Week 2024. Poster Session.

GIGA-Kids: APRIL Correlates With Proteinuria in IgAV

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pp04-blasco-biomarkers-in-iga-related-disorders
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